GALLAGHER, D.

Self-efficacy for managing dementia may protect against burden and depression in Alzheimer's caregivers

GALLAGHER, D., NI MHAOLAIN, A., CROSBY, L., RYAN, D., LACEY, L., COEN, R., F., WALSH, C., COAKLEY, D., WALSH, J., B., CUNNINGHAM, C., LAWLOR, B., A.
Aging & Mental Health
2011

In a study of eighty-four patient/caregiver dyads with mainly mild to moderate Alzheimer’s disease, Gallagher et al. (2011c) examined the relationship between self-efficacy for dementia management and symptoms of burden and depression among caregivers.

 They found that self-efficacy for symptom management of those with mild to moderate dementia directly impacts on the psychological health of caregivers, while among those with moderate to severe dementia, self-efficacy was more likely to mediate the relationship between the two.  They also found that self-efficacy may act as a buffer against the impact of behavioural symptoms on caregiver depression and burden.

Dependence and caregiver burden in Alzheimer’s disease and mild cognitive impairment (2011a)

Determinants of the desire to institutionalize in Alzheimer's caregivers(2011b)

Determinants of the desire to institutionalize in Alzheimer's caregivers

GALLAGHER, D., NI MHAOLAIN, A., CROSBY, L., RYAN, D., LACEY, L., COEN, R.F., WALSH, C., COAKLEY, D., WALSH, J.B., CUNNINGHAM, C., LAWLOR, B.A.
American Journal of Alzheimer's Disease and Other Dementias
2011

In a second paper from the same study Gallagher et al. (2011b) explored determinants of the desire to institutionalise (DI) among those caring for someone with Alzheimer’s disease.

 They asked whether potentially modifiable caregivers attributes were linked to DI and found that the most significant of these were caregiver burden and depression.  They also found an association between low caregiver self-efficacy and DI, and that caregivers with an emotion focused coping style were less likely to report DI.  The authors conclude that a multifactoral approach should be taken to reduce symptoms of burden and depression among caregivers. 

Dependence and caregiver burden in Alzheimer’s disease and mild cognitive impairment (2011a)

Self-efficacy for managing dementia may protect against burden and depression in Alzheimer's caregivers(2011c)

Dependence and caregiver burden in Alzheimer’s disease and mild cognitive impairment

GALLAGHER, D., NI MHAOLAIN, A., CROSBY, L., RYAN, D., LACEY, L., COEN, R.F., WALSH, C., COAKLEY, D., WALSH, J.B., CUNNINGHAM, C., LAWLOR, B.A.
American Journal of Alzheimer's Disease and Other Dementias
2011

One hundred participants with mostly mild to moderate dementia and their caregivers took part in this study by Gallagher et al (2011a), the objectives of which were to determine the impact of patient dependence on caregiver burden and to determine its value as a predictor of care

giver burden. The authors report functional decline and patient dependence as most predictive of caregiver burden in the earlier stages of dementia while neuropsychiatric or behavioural symptoms were most predictive as dementia progressed.  The authors also comment on the usefulness and easy administration of the dependence scale.

Determinants of the desire to institutionalize in Alzheimer's caregivers(2011b)

Self-efficacy for managing dementia may protect against burden and depression in Alzheimer's caregivers(2011c)

Anxiety and behavioural disturbances as markers of prodromal Alzheimer’s disease in patients with mild cognitive impairment

GALLAGHER, D., COEN, R., KILROY, D., BELINSKI, K., BRUCE, I., COAKLEY, D., WALSH, J.B., CUNNINGHAM, C., LAWLOR, B.A.
International journal of geriatric psychiatry
2011

In another article concerned with predicting conversion of MCI to Alzheimer’s disease, Gallagher et al. (2011) followed 169 patients with MCI over 27 months, 69 (43%) of whom converted to Alzheimer’s disease.

Neuropsychiatric symptoms were assessed with the Behavioural Pathology in Alzheimer’s disease (BEHAVE-AD) rating scale. Survival analysis revealed that patients with MCI who had symptoms of anticipated anxiety and purposeless activity were approximately twice as likely to have earlier conversion to Alzheimer’s disease than patients with MCI who did not have these symptoms. This finding was independent of age, gender and education. However, since this finding was not independent of cognitive status at baseline, it may be, as the authors conclude, that the neuropsychiatric symptoms of anticipated anxiety and purposeless activity are markers of severity of disease rather than independent predictors of disease progression.    

Detecting prodromal Alzheimer’s disease in mild cognitive impairment: utility of the CAMGOG and other neuropsychological predictors

GALLAGHER, D., MHAOLAIN, A., COEN, R., WALSH, C., KILROY, D., BELINSKI, K., BRUCE, I., COAKLEY, D., WALSH, J.B., CUNNINGHAM, C., LAWLOR, B.A
International journal of geriatric psychiatry
2010

Gallagher et al.

(2010) tested the usefulness of the Cambridge cognitive examination (CAMCOG), a well-established and widely used mini-neuropsychological battery, in detecting prodromal Alzheimer’s disease, and in particular which subtests of CAMCOG are predictive of conversion from mild cognitive impairment (MCI) to Alzheimer’s disease. The study compared CAMCOG and its subtests with an extended version of the delayed word recall (DWR) test. They followed 182 patients with MCI over a mean duration of 26 months, during which 75 (41%) converted to Alzheimer’s disease. The study found that tests of episodic memory were most predictive of conversion to Alzheimer’s disease and the composite memory score contained within CAMCOG was superior to tests of other cognitive domains assessed in CAMCOG. While the DWR test achieved the best predictive accuracy of conversion from MCI to Alzheimer’s disease, the CAMCOG composite memory score perfomed similarly well.  

Correlates of frailty In Alzheimer’s Disease and Mild Cognitive Impairment

NI MHAOLAIN, A., GALLAGHER, D., CROSBY, L., RYAN, D., LACEY, L., COEN, R., BRUCE, I., WALSH, J.B., CUNNINGHAM, C., LAWLOR, B.A.
Age and Ageing, 40(5)
2011

Ni Mhaolain et al. (2011) examine the relationship between frailty and a range of domains including age, comorbidity, course of illness, cognitive impairment, functional limitations and abnormalities of behaviour in a group of patients with AD and MCI.

The study found that 51% of the patients were robust or not-frail, with 49% at an intermediate or complete stage of frailty.  It suggests that escalating frailty is positively associated with increasing number of medical comorbidities and advancing age rather than being a marker of cognitive decline and severity of illness. The study suggests that optimising the management of co-morbid illness in people with dementia may play a role in minimizing the health impact of frailty in this group. 

Subscribe to RSS - GALLAGHER, D.